3-[(trimethylsilyl)ethynyl]pyridine

3-[(trimethylsilyl)ethynyl]pyridine - Names and Identifiers

Name	3-[(trimethylsilyl)ethynyl]pyridine
Synonyms	3-(TRIMETHYLSILYLETHYNYL)PYRI 3-(TRIMETHYLSILYLETHYNYL)PYRIDINE (3-PYRIDYLETHYNYL)TRIMETHYLSILANE 3-(Trimethlysilyl-ethynyl)pyridine 3-TRIMETHYLSILANYLETHYNYL-PYRIDINE 3-[(trimethylsilyl)ethynyl]pyridine 1-(3-PYRIDYL)-2-TRIMETHYLSILYLACETYLENE Pyridine, 3-[(trimethylsilyl)ethynyl]- (9CI)
CAS	80673-00-3
InChI	InChI=1/C10H13NSi/c1-12(2,3)8-6-10-5-4-7-11-9-10/h4-5,7,9H,1-3H3

3-[(trimethylsilyl)ethynyl]pyridine - Physico-chemical Properties

Molecular Formula	C10H13NSi
Molar Mass	175.3
Density	0.922g/mLat 25°C(lit.)
Boling Point	229°C(lit.)
Flash Point	202°F
Vapor Presure	0.19mmHg at 25°C
Appearance	Liquid
Color	Colorless to yellow
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Sensitive	Sensitive to heat, air and humidity
Refractive Index	n20/D 1.529(lit.)
MDL	MFCD01863744

3-[(trimethylsilyl)ethynyl]pyridine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29333990

3-[(trimethylsilyl)ethynyl]pyridine - Introduction

3-[(trimethylsilyl)ethynyl]pyridine is an organic compound with the chemical formula C11H15NSi. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 3-[(trimethylsilyl)ethynyl]pyridine is a colorless to light yellow liquid.
-Melting point: about -25 ℃.
-Boiling point: about 123-125 ℃.
-Density: about 0.876g/cm³.
-Solubility: Soluble in organic solvents such as benzene, ether and ethanol.

Use:
- 3-[(trimethylsilyl)ethynyl]pyridine can be used as an organic synthesis intermediate. It is often used to introduce trimethylsilylethynyl functional groups into organic synthesis reactions to change the molecular structure and properties.
-It can be used to synthesize compounds such as drugs, pesticides, dyes and polymer materials.

Preparation Method:
3-[(trimethylsilyl)ethynyl] The preparation method of pyridine is generally carried out by silylation reaction, and the specific steps are as follows:
1. take pyridine and trimethylsilylation reagent (such as trimethylchlorosilane) reaction in organic solvent.
2. After the reaction, the target product was purified by distillation and crystallization.

Safety Information:
- 3-[(trimethylsilyl)ethynyl]pyridine is an organic compound. Personal protective measures should be taken during operation, such as wearing protective gloves and protective glasses.
-When storing and handling this compound, avoid contact with fire and avoid the generation of harmful gases.
-In case of accidental contact with eyes, skin or in the mouth of the clothing, rinse immediately with plenty of water and seek medical help.
-When using and disposing of the compound, follow the relevant safety procedures and regulations to ensure personal safety and environmental safety.

Last Update：2024-04-09 15:18:00